CHEBI:51038 - minaprine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name minaprine
ChEBI ID CHEBI:51038
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB4686336, ZINC000019796082
Download Molfile XML SDF
Formula C17H22N4O
Net Charge 0
Average Mass 298.38294
Monoisotopic Mass 298.17936
InChI InChI=1S/C17H22N4O/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21/h2-6,13H,7-12H2,1H3,(H,18,20)
InChIKey LDMWSLGGVTVJPG-UHFFFAOYSA-N
SMILES Cc1cc(nnc1NCCN1CCOCC1)-c1ccccc1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): serotonin uptake inhibitor
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
cholinergic drug
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
Application(s): antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
serotonin uptake inhibitor
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
cholinergic drug
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
antiparkinson drug
A drug used in the treatment of Parkinson's disease.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing minaprine (CHEBI:51038) has role antidepressant (CHEBI:35469)
minaprine (CHEBI:51038) has role antiparkinson drug (CHEBI:48407)
minaprine (CHEBI:51038) has role cholinergic drug (CHEBI:38323)
minaprine (CHEBI:51038) has role dopamine uptake inhibitor (CHEBI:51039)
minaprine (CHEBI:51038) has role serotonin uptake inhibitor (CHEBI:50949)
minaprine (CHEBI:51038) is a morpholines (CHEBI:38785)
minaprine (CHEBI:51038) is a pyridazines (CHEBI:37921)
minaprine (CHEBI:51038) is a secondary amine (CHEBI:32863)
Incoming minaprine hydrochloride (CHEBI:51040) has part minaprine (CHEBI:51038)
IUPAC Name
4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
INNs Sources
minaprina ChEBI
minaprine ChEBI
minaprinum ChEBI
Synonyms Sources
4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine ChemIDplus
4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin ChemIDplus
N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine ChemIDplus
Manual Xrefs Databases
1812 DrugCentral
D05039 KEGG DRUG
DB00805 DrugBank
DE2229215 Patent
LSM-2037 LINCS
US4169158 Patent
View more database links
Registry Numbers Types Sources
1219740 Beilstein Registry Number Beilstein
25905-77-5 CAS Registry Number ChemIDplus
Last Modified
22 February 2017