CHEBI:43871 - fasudil

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ChEBI Name fasudil
ChEBI ID CHEBI:43871
Definition An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Roles Classification
Biological Role(s): EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine.
calcium channel blocker
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Application(s): geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
vasodilator agent
A drug used to cause dilation of the blood vessels.
nootropic agent
Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
Related Structures
fasudil is a Structural Derivative of
sulfonic acid
Mass : 82.08008
Formula : H2O3S
29214 		oxoacid
Definition : A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
fasudil is a Conjugate Base of
fasudil(1+)
Mass : 292.380
Formula : C14H18N3O2S
180694
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