R24 (CHEBI:79310)

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ChEBI Name	R24

ChEBI ID	CHEBI:79310

Definition	A member of the class of quinazolines that is quinazoline-2,4-diamine in which one of the hydrogens attached to the amino group at position 2 is replaced by a 3-chloro-4-methylphenyl group. It has been found to stimulate the immune defences of the nematode Caenorhabditis elegans, so affording protection from bacterial infection.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C15H13ClN4

Net Charge

Average Mass

284.74400

Monoisotopic Mass

284.08287

InChI

InChI=1S/C15H13ClN4/c1-9-6-7-10(8-12(9)16)18-15-19-13-5-3-2-4-11(13)14(17)20-15/h2-8H,1H3,(H3,17,18,19,20)

InChIKey

LFMFPKKYRXFHHZ-UHFFFAOYSA-N

SMILES

Cc1ccc(Nc2nc(N)c3ccccc3n2)cc1Cl

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system.

Application(s):	immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system.

ChEBI Ontology
Outgoing	R24 (CHEBI:79310) has role immunomodulator (CHEBI:50846) R24 (CHEBI:79310) is a monochlorobenzenes (CHEBI:83403) R24 (CHEBI:79310) is a primary amino compound (CHEBI:50994) R24 (CHEBI:79310) is a quinazolines (CHEBI:38530) R24 (CHEBI:79310) is a secondary amino compound (CHEBI:50995) R24 (CHEBI:79310) is a substituted aniline (CHEBI:48975)

IUPAC Name

N²-(3-chloro-4-methylphenyl)quinazoline-2,4-diamine

Synonyms

Sources

2-N-(3-chloro-4-methylphenyl) quinazoline-2,4-diamine

ChEBI

RPW-24

Note: (2016-02-08) Former name, subsequently changed to R24 at the request of the researcher who first published the molecule.

ChEBI

Citation	Type	Source
22719261	PubMed citation	Europe PMC

Last Modified

08 February 2016