alosetron hydrochloride (CHEBI:53783)

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ChEBI Name	alosetron hydrochloride

ChEBI ID	CHEBI:53783

Definition	The hydrochloride salt of alosetron.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

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Formulae

C17H18N4O.HCl
C17H19ClN4O

Net Charge

Average Mass

330.81200

Monoisotopic Mass

330.12474

InChI

InChI=1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H

InChIKey

FNYQZOVOVDSGJH-UHFFFAOYSA-N

SMILES

[H+].[Cl-].Cc1[nH]cnc1CN1CCc2c(C1=O)c1ccccc1n2C

Roles Classification
Biological Role(s):	serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.

Application(s):	antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.

ChEBI Ontology
Outgoing	alosetron hydrochloride (CHEBI:53783) has part alosetron (CHEBI:253342) alosetron hydrochloride (CHEBI:53783) has role antiemetic (CHEBI:50919) alosetron hydrochloride (CHEBI:53783) has role serotonergic antagonist (CHEBI:48279) alosetron hydrochloride (CHEBI:53783) is a hydrochloride (CHEBI:36807)

IUPAC Name

5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one hydrochloride

INN	Source
alosetron	ChEBI

Synonyms	Sources
2,3,4,5-Tetrahydro-5-methyl-2-((5-methylimidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one monohydrochloride	ChemIDplus
Alosetron HCl	DrugBank

Last Modified

13 June 2014