(+)-SKF-10,047 (CHEBI:228223)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	(+)-SKF-10,047

ChEBI ID	CHEBI:228223

Definition	The (+)-stereoisomer of SKF-10,047.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C17H23NO

Net Charge

Average Mass

257.377

Monoisotopic Mass

257.17796

InChI

InChI=1S/C17H23NO/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17/h4-6,11-12,16,19H,1,7-10H2,2-3H3/t12-,16+,17+/m1/s1

InChIKey

LGQCVMYAEFTEFN-DQYPLSBCSA-N

SMILES

C[C@@H]1[C@@H]2CC3=C(C=C(O)C=C3)[C@@]1(C)CCN2CC=C

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. (via SKF-10,047 ) opioid receptor antagonist An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists. (via SKF-10,047 )

Application(s):	sigma-1 receptor agonist A sigma receptor modulator that activates the sigma-1 receptor. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. (via SKF-10,047 ) opioid receptor antagonist An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists. (via SKF-10,047 )

ChEBI Ontology
Outgoing	(+)-SKF-10,047 (CHEBI:228223) has role neuroprotective agent (CHEBI:63726) (+)-SKF-10,047 (CHEBI:228223) has role sigma-1 receptor agonist (CHEBI:228237) (+)-SKF-10,047 (CHEBI:228223) is a SKF-10,047 (CHEBI:228203)

IUPAC Name

(2S,6S,11S)-6,11-dimethyl-3-(prop-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol

Synonyms	Sources
(+)-N-allylnormetazocine	ChEBI
(+)-NANM	ChEBI
(+)-SKF 10,047	ChEBI
(+)-SKF 10047	ChEBI
(+)SKF 10,047	ChEBI
(2S,6S,11S)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propen-1-yl)-2,6-methano-3-benzazocin-8-ol	ChEBI
d-N-allylnormetazocine	ChEBI
d-SKF 10047	ChEBI

Registry Number	Type	Source
58640-82-7	CAS Registry Number	ChEBI

Last Modified

17 November 2023