dexbrompheniramine (CHEBI:59269)

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ChEBI Name	dexbrompheniramine

ChEBI ID	CHEBI:59269

Definition	The (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H₁ receptor antagonist, it is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C16H19BrN2

Net Charge

Average Mass

319.23900

Monoisotopic Mass

318.07316

InChI

InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1

InChIKey

ZDIGNSYAACHWNL-HNNXBMFYSA-N

SMILES

CN(C)CC[C@@H](c1ccc(Br)cc1)c1ccccn1

Roles Classification
Biological Role(s):	H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. (via brompheniramine )

Application(s):	H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. (via brompheniramine ) anti-allergic agent A drug used to treat allergic reactions. (via brompheniramine )

ChEBI Ontology
Outgoing	dexbrompheniramine (CHEBI:59269) has role anti-allergic agent (CHEBI:50857) dexbrompheniramine (CHEBI:59269) has role H₁-receptor antagonist (CHEBI:37955) dexbrompheniramine (CHEBI:59269) is a brompheniramine (CHEBI:3183)

Incoming	dexbrompheniramine maleate (CHEBI:59273) has part dexbrompheniramine (CHEBI:59269)

IUPAC Name

(3S)-3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine

Last Modified

22 February 2017