CHEBI:6757 - mephenytoin

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ChEBI Name mephenytoin ChEBI ID CHEBI:6757 Definition An imidazolidine-2,4-dione (hydantoin) in which the imidazolidine nucleus carries a methyl group at N-3 and has ethyl and phenyl substituents at C-5. An anticonvulsant, it is no longer available in the USA or the UK but is still studied largely because of its interesting hydroxylation polymorphism. Stars This entity has been manually annotated by the ChEBI Team. Secondary ChEBI IDs CHEBI:91914 Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C12H14N2O2 Net Charge 0 Average Mass 218.252 Monoisotopic Mass 218.10553 InChI InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16) InChIKey GMHKMTDVRCWUDX-UHFFFAOYSA-N SMILES CCC1(C(=O)N(C(=O)N1)C)C2=CC=CC=C2 Roles Classification Application(s): anticonvulsant A drug used to prevent seizures or reduce their severity. View more via ChEBI Ontology ChEBI Ontology Outgoing mephenytoin (CHEBI:6757) has role anticonvulsant (CHEBI:35623) mephenytoin (CHEBI:6757) is a imidazolidine-2,4-dione (CHEBI:24628) IUPAC Name 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione INNs Sources mefenitoína WHO MedNet mephenytoin KEGG DRUG méphénytoïne WHO MedNet mephenytoinum WHO MedNet Synonyms Sources DL-Mephenytoin DrugCentral methylphenetoin DrugCentral phenylethylmethylhydantoin DrugCentral Manual Xrefs Databases 1695 DrugCentral D00375 KEGG DRUG LSM-1852 LINCS Mephenytoin Wikipedia View more database links Registry Numbers Types Sources 17282 Reaxys Registry Number Reaxys 50-12-4 CAS Registry Number DrugCentral Citations Types Sources 11422005 PubMed citation Europe PMC 15282764 PubMed citation Europe PMC 25797720 PubMed citation Europe PMC 29438107 PubMed citation Europe PMC Last Modified 20 June 2018