Services
Research
Training
Industry
About us
ChEBI
Examples:
iron*
,
InChI=1S/CH4O/c1-2/h2H,1H3
,
caffeine
Advanced
Home
Advanced Search
Browse
Documentation
Download
Tools
About ChEBI
Submit
Contact us
DiNA
Statistics
Entity of the Month
Periodic Table
Ontology
Train online
User Manual
Annotation Manual
Developer Manual
FAQ's
BiNChE
libChEBI
Web Services
ChEBI
> Main
CHEBI:421843 - (−)-carbovir
Main
ChEBI Ontology
Automatic Xrefs
Reactions
Pathways
Models
ChEBI Name
(−)-carbovir
ChEBI ID
CHEBI:421843
ChEBI ASCII Name
(-)-carbovir
Definition
The (active) (−)-enantiomer of the carbocyclic analogue of 2',3'-dideoxy-2',3'-didehydroguanosine.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download
Molfile
XML
SDF
Find compounds which contain this structure
Find compounds which resemble this structure
Take structure to the Advanced Search
more structures >>
Molfile
Formula
C11H13N5O2
Net Charge
0
Average Mass
247.25320
Monoisotopic Mass
247.10692
InChI
InChI=1S/C11H13N5O2/c12-
11-
14-
9-
8(10(18)
15-
11)
13-
5-
16(9)
7-
2-
1-
6(3-
7)
4-
17/h1-
2,5-
7,17H,3-
4H2,(H3,12,14,15,18)
/t6-
,7+/m1/s1
InChIKey
XSSYCIGJYCVRRK-RQJHMYQMSA-N
SMILES
Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1C[C@H](CO)C=C1
Roles Classification
Biological Role
(s):
HIV-1 reverse transcriptase inhibitor
An entity which inhibits the activity of HIV-1 reverse transcriptase.
(via
carbovir
)
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
(−)-carbovir (
CHEBI:421843
)
has role
HIV-1 reverse transcriptase inhibitor (
CHEBI:53756
)
(−)-carbovir (
CHEBI:421843
)
is a
carbovir (
CHEBI:202940
)
Incoming
carbovir diphosphate (
CHEBI:64172
)
has functional parent
(−)-carbovir (
CHEBI:421843
)
carbovir monophosphate (
CHEBI:64116
)
has functional parent
(−)-carbovir (
CHEBI:421843
)
carbovir triphosphate (
CHEBI:64174
)
has functional parent
(−)-carbovir (
CHEBI:421843
)
IUPAC Name
2-
amino-
9-
[(1
R
,4
S
)-
4-
(hydroxymethyl)cyclopent-
2-
en-
1-
yl]-
1,9-
dihydro-
6
H
-
purin-
6-
one
Synonyms
Sources
(1
R
-
cis
)-
2-
amino-
1,9-
dihydro-
9-
(4-
(hydroxymethyl)-
2-
cyclopenten-
1-
yl)-
6
H
-
purin-
6-
one
ChEBI
2-amino-9-[(1
R
,4
S
)-4-(hydroxymethyl)cyclopent-2-en-1-yl]-9
H
-purin-6-ol
IUPAC
carbovir
ChEBI
CBV
ChEBI
Registry Number
Type
Source
120443-30-3
CAS Registry Number
ChemIDplus
Citations
Types
Sources
15887959
PubMed citation
ChEMBL
17373782
PubMed citation
ChEMBL
18549801
PubMed citation
Europe PMC
Last Modified
14 March 2012