OntologiesefoclassesEFO:0003918   
obstructive sleep apnea
http://www.ebi.ac.uk/efo/EFO_0003918

A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

A disorder characterized by recurrent episodic disruptions of breathing during sleep. It is caused by the intermittent relaxation of pharyngeal muscles leading to the narrowing or complete blockage of the upper airway. This results in compensatory arousal from sleep to breathe again. An anatomically narrow airway from body habitus or enlarged pharyngeal structures may also predispose to obstruction. Clinical presentation usually includes snoring, daytime sleepiness, difficulty concentrating and fatigue. Clinical course may progress to chronic hypoxemia with cardiovascular and cerebrovascular sequelae.

Cessation of air flow during sleep due to upper airway obstruction.

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Exact Synonyms
Apnea, Obstructive Sleep
Apneas, Obstructive Sleep
obstructive sleep apnea syndrome
Obstructive Sleep Apnea Syndrome
obstructive sleep apnea
Obstructive Sleep Apneas
Sleep Apnea Syndrome, Obstructive
Sleep Apnea, Obstructive
Sleep Apneas, Obstructive
Syndrome, Obstructive Sleep Apnea
Syndrome, Sleep Apnea, Obstructive
Syndrome, Upper Airway Resistance, Sleep Apnea
Upper Airway Resistance Sleep Apnea Syndrome
Related Synonyms
apnea, obstructive sleep
Apneas, obstructive sleep
obstructive sleep Apneas
Osa
OSAHS
sleep apnea hypopnea syndrome
sleep apnea syndrome, obstructive
sleep apnea/hypopnea syndrome
sleep Apneas, obstructive
syndrome, obstructive sleep apnea
syndrome, sleep apnea, obstructive
syndrome, upper airway resistance, sleep apnea
upper airway resistance sleep apnea syndrome