H
IPR035910

RyR/IP3 receptor binding core, RIH domain superfamily

InterPro entry
Short nameRyR/IP3R_RIH_dom_sf
Overlapping entries
 
RIH domain (IPR000699)

Description

Ryanodine (RyR) and Inositol 1,4,5-trisphosphate (IP3) receptors are intracellular Ca2+-release channels. The RIH (RyR and IP3R Homology) domain is an extracellular domain from these two types of calcium channels. This domain may form a binding site for IP3
[1]
.

The structure of the IP3 receptor consists of two (curved) layers α/α and a right-handed superhelix.

References

1.Novel repeats in ryanodine and IP3 receptors and protein O-mannosyltransferases. Ponting CP. Trends Biochem. Sci. 25, 48-50, (2000). View articlePMID: 10664581

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