IPR035910
RyR/IP3 receptor binding core, RIH domain superfamily
InterPro entry
Short name | RyR/IP3R_RIH_dom_sf |
Overlapping entries |
Description
Ryanodine (RyR) and Inositol 1,4,5-trisphosphate (IP3) receptors are intracellular Ca2+-release channels. The RIH (RyR and IP3R Homology) domain is an extracellular domain from these two types of calcium channels. This domain may form a binding site for IP3
[1].
The structure of the IP3 receptor consists of two (curved) layers α/α and a right-handed superhelix.
References
1.Novel repeats in ryanodine and IP3 receptors and protein O-mannosyltransferases. Ponting CP. Trends Biochem. Sci. 25, 48-50, (2000). View articlePMID: 10664581
Contributing Member Database Entry
- SUPERFAMILY:SSF100909