Compound three letter code : CRN
 
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Entry Information
Entry status  (1)
REL
(6)
 
Experimental methods  (2)
Electron Microscopy
(3)
X-ray diffraction
(3)
 
Authors  (30)
Bobkov A
(3)
Demir M
(3)
Fujimoto L
(3)
Hitosugi T
(3)
Koepping L
(3)
Li Y
(3)
Sergienko E
(3)
Zhao J
(3)
Ito K
(2)
Nakajima Y
(2)
Yoshimoto T
(2)
Bong SM
(1)
Chi YM
(1)
Haratake M
(1)
Hwang KY
(1)
Inoue T
(1)
Kanada N
(1)
Lee KS
(1)
Matsubara F
(1)
Matsushita H
(1)
Moon JH
(1)
Nakamura KT
(1)
Nam KH
(1)
Nishiya Y
(1)
Oyama H
(1)
Tanaka N
(1)
Wu YF
(1)
Xu Y
(1)
Yamashita K
(1)
Yamazawa R
(1)
 
Homo / hetero assembly  (1)
homo
(6)
 
Assembly composition  (1)
protein structure
(6)
 
Assembly polymer count  (3)
octamer
(3)
hexamer
(2)
dimer
(1)
 
Resolution distribution
1.5 - 2
(3)
2.0 - 2.5
(3)
 
Release year distribution
2000 - 2005
(1)
2005 - 2010
(2)
2010 - 2015
(1)
2020 - 2025
(3)
2025 - 2030
(3)
 
Journal  (3)
Structure
(3)
J Mol Biol
(2)
FEBS Lett
(1)
 
Macromolecules
Organism superkingdom  (2)
Eukaryota
(4)
Bacteria
(2)
 
Organism name  (3)
Homo sapiens
(4)
Pseudomonas putida
(1)
Pseudomonas sp.
(1)
 
Molecule name  (13)
Acidic-type mitochondrial creatine kinase
(3)
Creatine kinase U-type, mitochondrial
(3)
Mia-CK
(3)
U-MtCK
(3)
Ubiquitous mitochondrial creatine kinase
(3)
Creatininase
(2)
Creatinine amidohydrolase
(2)
B-CK
(1)
Brain creatine kinase
(1)
CPK-B
(1)
Creatine kinase B chain
(1)
Creatine kinase B-type
(1)
Creatine phosphokinase B-type
(1)
 
Molecule type  (1)
Protein
(6)
 
Gene names  (6)
CKMT
(3)
CKMT1A
(3)
CKMT1B
(3)
crnA
(2)
CKB
(1)
CKBB
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 6 of 6
Entries 1 to 6 of 6
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Cryo-EM structure of E227Q variant of uMtCK1 incubated with ADP and phosphocreatine at pH 8.0
Demir M, Koepping L, Zhao J, Sergienko E
Structure (2025) [PMID: 39904336  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: MG    CRN    ADP    ADP    CRN    MG    PO4   
Assembly name: Creatine kinase U-type, mitochondrial (Preferred)   search this complex
PDBe complex ID: PDB-CPX-146261 (Preferred)   search this ID
PDBe-KB: P12532    P12532   
Electron Microscopy
2.44Å resolution
Released: 12 Feb 2025
Model geometry
Fit model/data
Data not analysed
9b0u
9b0u
9b0u
Cryo-EM structure of E227Q variant of uMtCK1 in complex with transition state analog
Demir M, Koepping L, Zhao J, Sergienko E
Structure (2025) [PMID: 39904336  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: NO3    MG    CRN    ADP    ADP    CRN    MG   
Assembly name: Creatine kinase U-type, mitochondrial (Preferred)   search this complex
PDBe complex ID: PDB-CPX-146261 (Preferred)   search this ID
PDBe-KB: P12532    P12532   
Electron Microscopy
2.3Å resolution
Released: 12 Feb 2025
Model geometry
Fit model/data
Data not analysed
9b0t
9b0t
9b0t
Cryo-EM structure of human uMtCK1 in complex with transition state analog
Demir M, Koepping L, Zhao J, Sergienko E
Structure (2025) [PMID: 39904336  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: MG    CRN    ADP    ADP    CRN    MG   
Assembly name: Creatine kinase U-type, mitochondrial (Preferred)   search this complex
PDBe complex ID: PDB-CPX-146261 (Preferred)   search this ID
PDBe-KB: P12532    P12532   
Electron Microscopy
2.2Å resolution
Released: 12 Feb 2025
Model geometry
Fit model/data
Data not analysed
9b14
9b14
9b14
creatininase-product complex
Yoshimoto T, Tanaka N, Kanada N, Inoue T, Nakajima Y, Haratake M, Nakamura KT, Xu Y, Ito K
J Mol Biol (2004) [PMID: 15003455  ]
Source organism: Pseudomonas sp.  
Assembly composition: protein only structure
Bound ligands: CRN    ZN    MN    SO4    ZN    CRN    MN   
Assembly name: Creatinine amidohydrolase (Preferred)   search this complex
PDBe complex ID: PDB-CPX-160738 (Preferred)   search this ID
PDBe-KB: P83772   
X-ray diffraction
1.6Å resolution
Released: 27 Jan 2004
Model geometry
Fit model/data
Data not deposited
1v7z
1v7z
1v7z
E122Q mutant creatininase complexed with creatine
Nakajima Y, Yamashita K, Ito K, Yoshimoto T
J Mol Biol (2010) [PMID: 20043918  ]
Source organism: Pseudomonas putida  
Assembly composition: protein only structure
Bound ligands: CRN    ZN    SO4    ZN    CRN   
Assembly name: Creatinine amidohydrolase (Preferred)   search this complex
PDBe complex ID: PDB-CPX-160738 (Preferred)   search this ID
PDBe-KB: P83772   
X-ray diffraction
2Å resolution
Released: 9 Feb 2010
Model geometry
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3a6j
3a6j
3a6j
Crystal structure of Human Brain-type Creatine Kinase
Bong SM, Moon JH, Hwang KY
FEBS Lett (2008) [PMID: 18977227  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: NO3    ACT    MG    CRN    ADP    ADP    CRN    MG    ACT   
Assembly name: Creatine kinase B-type (Preferred)   search this complex
PDBe complex ID: PDB-CPX-146122 (Preferred)   search this ID
PDBe-KB: P12277   
X-ray diffraction
2Å resolution
Released: 4 Nov 2008
Model geometry
Fit model/data
3b6r
3b6r
3b6r
Entries 1 to 6 of 6
Entries 1 to 6 of 6