Entry status  (1)

REL

(17)

Experimental methods  (2)

X-ray diffraction

(16)

Electron Microscopy

(1)

Authors  (195)

Christianson DW

(5)

Albrecht D

(3)

Berndt L

(3)

Deardorff MA

(3)

Decroos C

(3)

Dorre B

(3)

Dörre B

(3)

Girbardt B

(3)

Graf LG

(3)

Hocking DM

(3)

Hofmann K

(3)

Janetzky M

(3)

Jebeli L

(3)

Lammers M

(3)

Moreno-Yruela C

(3)

Olsen CA

(3)

Palm GJ

(3)

Qin C

(3)

Schmoker O

(3)

Schmöker O

(3)

Schulze S

(3)

Sievers S

(3)

Strugnell RA

(3)

Wang N

(3)

Weis DM

(3)

Zuhlke D

(3)

Zühlke D

(3)

Bowman CB

(2)

Bowman CM

(2)

Christianson KE

(2)

Moser J-AS

(2)

Moser JA

(2)

Alfieri C

(1)

Allali-Hassani A

(1)

Andrade L

(1)

Arrowsmith CH

(1)

Arvai A

(1)

Bochkarev A

(1)

Breslow R

(1)

Buck IM

(1)

Buggy JJ

(1)

Caby S

(1)

Casero Jr RA

(1)

Casero RA

(1)

Cavarelli J

(1)

Chi E

(1)

Choudhary JS

(1)

Cleasby A

(1)

Cohen A

(1)

Cons BD

(1)

Cui K

(1)

Cura V

(1)

Dawson L

(1)

Dickmanns A

(1)

Donigian JR

(1)

Dougan DR

(1)

East C

(1)

Edwards AM

(1)

Fedorowicz G

(1)

Ficner R

(1)

Finnin MS

(1)

Flicke B

(1)

Foley JR

(1)

Fong R

(1)

Futamura T

(1)

Geraldy MNE

(1)

Goto S

(1)

Griffiths-Jones C

(1)

Gunkel N

(1)

Gunzner J

(1)

Géraldy MNE

(1)

Hai Y

(1)

Hashimoto T

(1)

Hauser A

(1)

Hauser AT

(1)

Heightman TD

(1)

Heise CE

(1)

Herbst-Gervasoni CJ

(1)

Hildmann C

(1)

Ho JD

(1)

Huang J

(1)

Ishikawa S

(1)

Ito H

(1)

Jennings AJ

(1)

Jung M

(1)

Kaminker JS

(1)

Kaneko Y

(1)

Kannan S

(1)

Katz BA

(1)

Kawato T

(1)

Klinke G

(1)

Knuth MW

(1)

Koliopolous MG

(1)

Koliopoulos MG

(1)

Kondo K

(1)

Koth CM

(1)

Krantz ID

(1)

Kurihara N

(1)

Kuster B

(1)

Kwiatkowski NP

(1)

 

More...

Homo / hetero assembly  (2)

homo

(16)

hetero

(1)

Assembly composition  (2)

protein structure

(16)

protein/protein complex

(1)

Assembly polymer count  (4)

monomer

(13)

tetramer

(2)

dimer

(1)

trimer

(1)

Resolution distribution

1.0 - 1.5

(1)

1.5 - 2

(9)

2.0 - 2.5

(5)

2.5 - 3

(2)

Release year distribution

1995 - 2000

(1)

2000 - 2005

(2)

2005 - 2010

(2)

2010 - 2015

(5)

2015 - 2020

(3)

2020 - 2025

(7)

Journal  (12)

Nat Commun

(4)

ACS Chem Biol

(2)

J Biol Chem

(2)

ACS Med Chem Lett

(1)

J Am Chem Soc

(1)

J Mol Biol

(1)

J Struct Biol

(1)

Nat Chem Biol

(1)

Nature

(1)

PLoS Pathog

(1)

Structure

(1)

To be published

(1)

Organism superkingdom  (2)

Eukaryota

(12)

Bacteria

(5)

Organism name  (8)

Homo sapiens

(9)

Danio rerio

(2)

Alcaligenaceae bacterium FB188

(1)

Aquifex aeolicus

(1)

Klebsiella pneumoniae subsp. ozaenae

(1)

Rhizorhabdus wittichii DC-6

(1)

Schistosoma mansoni

(1)

Vibrio cholerae

(1)

Molecule name  (36)

Histone deacetylase 8

(5)

HD8

(4)

Protein deacetylase HDAC8

(4)

Protein decrotonylase HDAC8

(4)

HD2

(3)

Histone deacetylase 2

(3)

Histone deacetylase domain-containing protein

(3)

Protein deacylase HDAC2

(3)

Acetoin utilization protein

(1)

Acetoin utilization protein AcuC

(1)

Deacetylase

(1)

Dimethoate hydrolase

(1)

HD7

(1)

HD7a

(1)

HDAC-like amidohydrolase

(1)

HDAH

(1)

Histone deacetylase

(1)

Histone deacetylase 10

(1)

Histone deacetylase 6

(1)

Histone deacetylase 7

(1)

Histone deacetylase 7A

(1)

Histone deacetylase complex subunit Sin3b

(1)

Histone deacetylase-like amidohydrolase

(1)

LTA-4 hydrolase

(1)

Leukotriene A(4) hydrolase

(1)

Leukotriene A-4 hydrolase

(1)

PHD factor 1

(1)

PHD finger protein 12

(1)

Paired amphipathic helix protein Sin3b

(1)

Pf1

(1)

Polyamine deacetylase HDAC10

(1)

Protein deacetylase HDAC7

(1)

Transcriptional corepressor Sin3b

(1)

Tripeptide aminopeptidase LTA4H

(1)

UBP-type domain-containing protein

(1)

histone deacetylase

(1)

Molecule type  (1)

Protein

(17)

Gene names  (22)

HDAC8

(5)

CDA07

(4)

HDACL1

(4)

HDAC2

(3)

hdaH

(2)

BC353_06500

(1)

HDAC7

(1)

HDAC7A

(1)

KIAA0700

(1)

KIAA1523

(1)

LTA4

(1)

LTA4H

(1)

NCTC10313_02007

(1)

NCTC5050_05964

(1)

PHF12

(1)

SIN3B

(1)

acuC1

(1)

aq_1023

(1)

dmhA

(1)

hdaH1

(1)

hdac10

(1)

hdac6

(1)

Interacting Molecules  (3)

Histone deacetylase 2

(1)

PHD finger protein 12

(1)

Paired amphipathic helix protein Sin3b

(1)

Interacting ligands  (20)

SHH : OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE

(17)

ZN : ZINC ION

(17)

K : POTASSIUM ION

(11)

GOL : GLYCEROL

(5)

CA : CALCIUM ION

(3)

EDO : 1,2-ETHANEDIOL

(3)

ACT : ACETATE ION

(2)

NA : SODIUM ION

(2)

PEG : DI(HYDROXYETHYL)ETHER

(2)

PG4 : TETRAETHYLENE GLYCOL

(2)

CL : CHLORIDE ION

(1)

DMF : DIMETHYLFORMAMIDE

(1)

IMD : IMIDAZOLE

(1)

KK0 : (5~{S})-5-(4-chlorophenyl)pyrrolidin-2-one

(1)

KZF : 2-(cyclohexylazaniumyl)ethanesulfonate

(1)

MG : MAGNESIUM ION

(1)

NHE : 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID

(1)

OCA : OCTANOIC ACID (CAPRYLIC ACID)

(1)

PO4 : PHOSPHATE ION

(1)

YB : YTTERBIUM (III) ION

(1)

EC number / name  (5)

3.5.1.98 : Histone deacetylase

(10)

3.3.2.6 : Leukotriene-A(4) hydrolase

(1)

3.4.11.4 : Tripeptide aminopeptidase

(1)

3.5.1.48 : Acetylspermidine deacetylase

(1)

3.5.1.62 : Acetylputrescine deacetylase

(1)

Biological function  (36)

histone deacetylase activity

(13)

hydrolase activity

(11)

metal ion binding

(9)

protein binding

(7)

protein lysine deacetylase activity

(7)

DNA-binding transcription factor binding

(6)

histone deacetylase activity, hydrolytic mechanism

(6)

histone decrotonylase activity

(6)

protein decrotonylase activity

(6)

Hsp70 protein binding

(4)

Hsp90 protein binding

(4)

RNA binding

(3)

deacetylase activity

(3)

NF-kappaB binding

(2)

RNA polymerase II-specific DNA-binding transcription factor binding

(2)

chromatin binding

(2)

enzyme binding

(2)

heat shock protein binding

(2)

histone binding

(2)

histone deacetylase binding

(2)

nucleosomal DNA binding

(2)

promoter-specific chromatin binding

(2)

protein de-2-hydroxyisobutyrylase activity

(2)

protein lysine delactylase activity

(2)

transcription coregulator binding

(2)

zinc ion binding

(2)

acetylputrescine deacetylase activity

(1)

acetylspermidine deacetylase activity

(1)

aminopeptidase activity

(1)

epoxide hydrolase activity

(1)

leukotriene-A4 hydrolase activity

(1)

metalloaminopeptidase activity

(1)

metallopeptidase activity

(1)

peptidase activity

(1)

transcription corepressor activity

(1)

tripeptide aminopeptidase activity

(1)

Representative Structures

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