› 146d

Solution NMR

SOLUTION STRUCTURE OF THE MITHRAMYCIN DIMER-DNA COMPLEX

Released:
DOI: 10.2210/pdb146d/pdb
PDB entry 146d coloured by chain, ensemble of 2 models, front view.
PDB entry 146d coloured by chain, ensemble of 2 models, side view.
PDB entry 146d coloured by chain, ensemble of 2 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of the mithramycin dimer-DNA complex.
Sastry M, Patel DJ
Biochemistry 32 6588-604 (1993)
PMID: 8329387

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113336 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecules (3 distinct):
DNA (5'-D(*TP*CP*GP*CP*GP*A)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

Carbohydrate polymer : NEW Components: DDA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: DDA, DDL, MDA
Carbohydrate polymer
2 bound ligands:
Ligand MG 1 x MG
Ligand CRH 2 x CRH
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: MOLECULAR DYNAMICS, MATRIX RELAXATION
Expression system: Not provided

Quick links

Citations

10 review citations

The role of carbohydrates in biologically active natural products.
Weymouth-Wilson AC. (1997)
9 more

8 mentions without citation

The Growing Development of DNA Nanostructures for Potential Healthcare-Related Applications.
Mathur et al. (2019)
7 more