› 182d

X-ray diffraction
1.8Å resolution

DNA-NOGALAMYCIN INTERACTIONS: THE CRYSTAL STRUCTURE OF D(TGATCA) COMPLEXED WITH NOGALAMYCIN

Released:
DOI: 10.2210/pdb182d/pdb
PDB entry 182d coloured by chain, front view.
PDB entry 182d coloured by chain, side view.
PDB entry 182d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
DNA-nogalamycin interactions: the crystal structure of d(TGATCA) complexed with nogalamycin.
Smith CK, Davies GJ, Dodson EJ, Moore MH
Biochemistry 34 415-25 (1995)
PMID: 7819233

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113360 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*TP*GP*AP*TP*CP*A)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NGM 2 x NGM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X31
Spacegroup: P41212
Unit cell:
a: 37.2Å b: 37.2Å c: 70.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 not available 0.3
Expression system: Not provided

Quick links

Citations

2 review citations

The role of carbohydrates in biologically active natural products.
Weymouth-Wilson AC. (1997)
1 more

5 mentions without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)
4 more