› 1jnh

X-ray diffraction
2.85Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-226701 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig lambda-1 chain C region Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 212 amino acids
Theoretical weight: 22.74 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01843 (Residues: 1-102; Coverage: 97%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
monoclonal anti-estradiol 10G6D6 Fab heavy chain Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 218 amino acids
Theoretical weight: 23.54 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand ECO 4 x ECO
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 70.2Å b: 192.9Å c: 71.12Å
α: 90° β: 92.93° γ: 90°
R-values:
R R work R free
0.198 0.198 0.253

Quick links

Citations

15 citation in other articles

Cross-reactivity of steroid hormone immunoassays: clinical significance and two-dimensional molecular similarity prediction.
Krasowski et al. (2014)
14 more

3 mentions without citation

An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop.
Fanning et al. (2011)
2 more