› 1agz

Solution NMR

THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE

Released:
DOI: 10.2210/pdb1agz/pdb
PDB entry 1agz coloured by chain, front view.
PDB entry 1agz coloured by chain, side view.
PDB entry 1agz coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR.
Feng B, Zhou L, Passarelli M, Harris CM, Harris TM, Stone MP
Biochemistry 34 14021-36 (1995)
PMID: 7578000

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113421 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*CP*GP*GP*AP*CP*AP*RP*GP*AP*AP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 11 nucleotides
Theoretical weight: 3.54 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.29 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand R 1 x R

Experiments and Validation Details

Entry percentile scores
Refinement method: NOE-RESTRAINED MOLECULAR DYNAMICS/SIMULATED ANNEALING
Expression system: Not provided

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Citations

1 review citation

Chemistry and structural biology of DNA damage and biological consequences.
Stone et al. (2011)
7 other articles