› 1c49

Solution NMR

STRUCTURAL AND FUNCTIONAL DIFFERENCES OF TWO TOXINS FROM THE SCORPION PANDINUS IMPERATOR

Released:
DOI: 10.2210/pdb1c49/pdb
PDB entry 1c49 coloured by chain, ensemble of 18 models, front view.
PDB entry 1c49 coloured by chain, ensemble of 18 models, side view.
PDB entry 1c49 coloured by chain, ensemble of 18 models, top view.
Source organism: Pandinus imperator
Primary publication:
Structural and functional differences of two toxins from the scorpion Pandinus imperator.
Klenk KC, Tenenholz TC, Matteson DR, Rogowski RS, Blaustein MP, Weber DJ
Proteins 38 441-9 (2000)
PMID: 10707030

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157360 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin alpha-KTx 7.2 Chain: A
Molecule details ›
Chain: A
Length: 35 amino acids
Theoretical weight: 4.08 KDa
Source organism: Pandinus imperator
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P55928 (Residues: 1-35; Coverage: 100%)
Sequence domains: Scorpion short toxin, BmKK2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY SIMULATED ANNEALING
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Microbial production of toxins from the scorpion venom: properties and applications.
Amorim et al. (2018)
2 other articles

1 mention without citation

Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49.
Tsumoto et al. (2008)