› 1chz

X-ray diffraction
1.76Å resolution

A NEW NEUROTOXIN FROM BUTHUS MARTENSII KARSCH

Released:
DOI: 10.2210/pdb1chz/pdb
PDB entry 1chz coloured by chain, front view.
PDB entry 1chz coloured by chain, side view.
PDB entry 1chz coloured by chain, top view.
Source organism: Mesobuthus martensii
Primary publication:
Structure of a new neurotoxin from the scorpion Buthus martensii Karsch at 1.76 A.
He XL, Deng JP, Wang M, Zhang Y, Wang DC
Acta Crystallogr D Biol Crystallogr 56 25-33 (2000)
PMID: 10666623

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157693 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-like toxin BmK M2 Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.22 KDa
Source organism: Mesobuthus martensii
UniProt:
  • Canonical: P58488 (Residues: 1-64; Coverage: 100%)
Sequence domains: Scorpion toxin-like domain
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 36.64Å b: 37.31Å c: 37.95Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.19 0.248

Quick links

Citations

2 review citations

An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch.
Goudet et al. (2002)
1 more

1 mention without citation

Modular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.
Chugunov et al. (2013)