› 1cl5

X-ray diffraction
2.45Å resolution

CRYSTAL STRUCTURE OF PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA

Released:
DOI: 10.2210/pdb1cl5/pdb
PDB entry 1cl5 coloured by chain, front view.
PDB entry 1cl5 coloured by chain, side view.
PDB entry 1cl5 coloured by chain, top view.
Source organism: Daboia russelii pulchella
Primary publication:
Three-dimensional structure of a presynaptic neurotoxic phospholipase A2 from Daboia russelli pulchella at 2.4 A resolution.
Chandra V, Kaur P, Srinivasan A, Singh TP
J Mol Biol 296 1117-26 (2000)
PMID: 10686108

Function and Biology Details

Reaction catalysed: 
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157747 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Basic phospholipase A2 VRV-PL-VIIIa Chains: A, B
Molecule details ›
Chains: A, B
Length: 121 amino acids
Theoretical weight: 13.63 KDa
Source organism: Daboia russelii pulchella
UniProt:
  • Canonical: P59071 (Residues: 1-121; Coverage: 100%)
Sequence domains: Phospholipase A2
Structure domains: Phospholipase A2 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2221
Unit cell:
a: 77.048Å b: 92.347Å c: 77.049Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.188 0.267

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Citations

1 review citation

Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis.
Kang et al. (2011)
7 other articles

2 mentions without citation

Structural and dynamic determinants of protein-peptide recognition.
Dagliyan et al. (2011)
1 more