› 1cr8

Solution NMR

LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN COMPLEMENT REPEAT 8

Released:
DOI: 10.2210/pdb1cr8/pdb
PDB entry 1cr8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1cr8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1cr8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR solution structure of complement-like repeat CR8 from the low density lipoprotein receptor-related protein.
Huang W, Dolmer K, Gettins PG
J Biol Chem 274 14130-6 (1999)
PMID: 10318830

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Low-density lipoprotein receptor-related protein 1 515 kDa subunit Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07954 (Residues: 1059-1100; Coverage: 1%)
Gene names: A2MR, APR, LRP1
Sequence domains: Low-density lipoprotein receptor domain class A
Structure domains: Low-density Lipoprotein Receptor

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DYNAMICS ANNEALING
Expression system: Escherichia coli

Quick links

Citations

10 review citations

LRP: a multifunctional scavenger and signaling receptor.
Herz et al. (2001)
9 more

7 mentions without citation

The cellular receptor to human rhinovirus 2 binds around the 5-fold axis and not in the canyon: a structural view.
Hewat et al. (2000)
6 more