› 1d5t

X-ray diffraction
1.04Å resolution

GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM

Released:
DOI: 10.2210/pdb1d5t/pdb
PDB entry 1d5t coloured by chain, front view.
PDB entry 1d5t coloured by chain, side view.
PDB entry 1d5t coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling.
Luan P, Heine A, Zeng K, Moyer B, Greasely SE, Kuhn P, Balch WE, Wilson IA
Traffic 1 270-81 (2000)
PMID: 11208110

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149445 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rab GDP dissociation inhibitor alpha Chain: A
Molecule details ›
Chain: A
Length: 433 amino acids
Theoretical weight: 48.93 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P21856 (Residues: 1-431; Coverage: 96%)
Gene names: GDI1, RABGDIA
Sequence domains: GDP dissociation inhibitor
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P21
Unit cell:
a: 89.29Å b: 42.74Å c: 61.78Å
α: 90° β: 104.55° γ: 90°
R-values:
R R work R free
0.173 not available 0.209
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Targeting Rab GTPases to distinct membrane compartments.
Pfeffer et al. (2004)
4 more

9 mentions without citation

Structure prediction of domain insertion proteins from structures of individual domains.
Berrondo et al. (2008)
8 more