Function and Biology Details
Reaction catalysed:
Eliminative cleavage of dermatan sulfate containing (1->4)-beta-D-hexosaminyl and (1->3)-beta-D-glucurosonyl or (1->3)-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (Delta-UA-GalNAc-4S).
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Chondroitinase-B (preferred)
PDBe Complex ID:
PDB-CPX-175093 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Chondroitinase-B
Molecule details ›
Chain: A
Length: 506 amino acids
Theoretical weight: 56.39 KDa
Source organism: Pedobacter heparinus
UniProt:
Sequence domains: Chondroitinase B
Structure domains: Single-stranded right-handed beta-helix, Pectin lyase-like
Length: 506 amino acids
Theoretical weight: 56.39 KDa
Source organism: Pedobacter heparinus
UniProt:
- Canonical:
Q46079 (Residues: 1-506; Coverage: 100%)
Sequence domains: Chondroitinase B
Structure domains: Single-stranded right-handed beta-helix, Pectin lyase-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU
Spacegroup:
P21
