› 1e68

Solution NMR

Solution structure of bacteriocin AS-48

Released:
DOI: 10.2210/pdb1e68/pdb
PDB entry 1e68 coloured by chain, ensemble of 20 models, front view.
PDB entry 1e68 coloured by chain, ensemble of 20 models, side view.
PDB entry 1e68 coloured by chain, ensemble of 20 models, top view.
Source organism: Enterococcus faecalis
Primary publication:
Bacteriocin AS-48, a microbial cyclic polypeptide structurally and functionally related to mammalian NK-lysin.
González C, Langdon GM, Bruix M, Gálvez A, Valdivia E, Maqueda M, Rico M
Proc Natl Acad Sci U S A 97 11221-6 (2000)
PMID: 11005847

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175269 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AS-48 protein Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 7.18 KDa
Source organism: Enterococcus faecalis
UniProt:
  • Canonical: Q47765 (Residues: 36-105; Coverage: 67%)
Gene names: as-48, as48A, bacA
Sequence domains: Bacteriocin class IId cyclical uberolysin-like
Structure domains: Bacteriocin AS-48

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED MOLECULAR DYNAMICS

Quick links

Citations

27 review citations

Virulence factors of Enterococcus faecalis: relationship to endodontic disease.
Kayaoglu et al. (2004)
26 more

19 mentions without citation

Circular bacteriocins: biosynthesis and mode of action.
Gabrielsen et al. (2014)
18 more