› 1epf

X-ray diffraction
1.85Å resolution

CRYSTAL STRUCTURE OF THE TWO N-TERMINAL IMMUNOGLOBULIN DOMAINS OF THE NEURAL CELL ADHESION MOLECULE (NCAM)

Released:
DOI: 10.2210/pdb1epf/pdb
PDB entry 1epf coloured by chain, front view.
PDB entry 1epf coloured by chain, side view.
PDB entry 1epf coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structural basis of cell-cell adhesion by NCAM.
Kasper C, Rasmussen H, Kastrup JS, Ikemizu S, Jones EY, Berezin V, Bock E, Larsen IK
Nat Struct Biol 7 389-93 (2000)
PMID: 10802736

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146669 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neural cell adhesion molecule 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 191 amino acids
Theoretical weight: 21.41 KDa
Source organism: Rattus norvegicus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P13596 (Residues: 20-208; Coverage: 23%)
Gene names: Ncam, Ncam1
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 47.078Å b: 122.505Å c: 72.859Å
α: 90° β: 98.27° γ: 90°
R-values:
R R work R free
0.201 0.201 0.234
Expression system: Komagataella pastoris

Quick links

Citations

18 review citations

Polysialic acid-neural cell adhesion molecule in brain plasticity: from synapses to integration of new neurons.
Gascon et al. (2007)
17 more

6 mentions without citation

Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase sigma.
Aricescu et al. (2002)
5 more