› 1f62

Solution NMR

WSTF-PHD

Released:
DOI: 10.2210/pdb1f62/pdb
PDB entry 1f62 coloured by chain, ensemble of 20 models, front view.
PDB entry 1f62 coloured by chain, ensemble of 20 models, side view.
PDB entry 1f62 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor.
Pascual J, Martinez-Yamout M, Dyson HJ, Wright PE
J Mol Biol 304 723-9 (2000)
PMID: 11124022

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193787 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase BAZ1B Chain: A
Molecule details ›
Chain: A
Length: 51 amino acids
Theoretical weight: 5.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UIG0 (Residues: 1185-1235; Coverage: 3%)
Gene names: BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF
Sequence domains: PHD-finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Restrained molecular dynamics using AMBER-6 program
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

27 review citations

Ubiquitin: structures, functions, mechanisms.
Pickart et al. (2004)
26 more

10 mentions without citation

BAZ1B the Protean Protein.
Sharif et al. (2021)
9 more