› 1fhz

X-ray diffraction
2.2Å resolution

PSORALEN CROSS-LINKED D(CCGGTACCGG) FORMS HOLLIDAY JUNCTION

Released:
DOI: 10.2210/pdb1fhz/pdb
PDB entry 1fhz coloured by chain, front view.
PDB entry 1fhz coloured by chain, side view.
PDB entry 1fhz coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions.
Eichman BF, Mooers BH, Alberti M, Hearst JE, Ho PS
J Mol Biol 308 15-26 (2001)
PMID: 11302703

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113802 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand PSO 1 x PSO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: C2
Unit cell:
a: 72.116Å b: 23.651Å c: 36.182Å
α: 90° β: 112.64° γ: 90°
R-values:
R R work R free
0.236 0.228 0.311
Expression system: Not provided

Quick links

Citations

4 review citations

DNA interstrand crosslink repair in mammalian cells: step by step.
Muniandy et al. (2010)
3 more

3 mentions without citation

Interactions of small molecules with DNA junctions.
McQuaid et al. (2022)
2 more