› 1hvz

Solution NMR

RTD-1, A CYCLIC ANTIMICROBIAL DEFENSIN FROM RHESUS MACAQUE LEUKOCYTES

Released:
DOI: 10.2210/pdb1hvz/pdb
PDB entry 1hvz coloured by chain, ensemble of 20 models, front view.
PDB entry 1hvz coloured by chain, ensemble of 20 models, side view.
PDB entry 1hvz coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from Rhesus macaque leukocytes.
Trabi M, Schirra HJ, Craik DJ
Biochemistry 40 4211-21 (2001)
PMID: 11284676

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162229 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
THETA DEFENSIN 1 Chain: A
Molecule details ›
Chain: A
Length: 18 amino acids
Theoretical weight: 2.11 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing, explicit inclusion of water molecules
Expression system: Not provided

Quick links

Citations

23 review citations

Mammalian defensins in the antimicrobial immune response.
Selsted et al. (2005)
22 more

23 mentions without citation

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense.
Lai et al. (2009)
22 more