› 1ifq

X-ray diffraction
2.4Å resolution

Sec22b N-terminal domain

Released:
DOI: 10.2210/pdb1ifq/pdb
PDB entry 1ifq coloured by chain, front view.
PDB entry 1ifq coloured by chain, side view.
PDB entry 1ifq coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A novel snare N-terminal domain revealed by the crystal structure of Sec22b.
Gonzalez LC, Weis WI, Scheller RH
J Biol Chem 276 24203-11 (2001)
PMID: 11309394

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126625 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vesicle-trafficking protein SEC22b Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 16.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O08547 (Residues: 2-127; Coverage: 59%)
Gene names: Sec22b, Sec22l1
Sequence domains: Regulated-SNARE-like domain
Structure domains: Longin domain

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 50.244Å b: 57.056Å c: 99.009Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.231 0.274
Expression system: Escherichia coli

Quick links

Citations

10 review citations

SNAREs--engines for membrane fusion.
Jahn et al. (2006)
9 more

4 mentions without citation

The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development.
Gray et al. (2009)
3 more