› 1igf

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS

Released:
DOI: 10.2210/pdb1igf/pdb
PDB entry 1igf coloured by chain, front view.
PDB entry 1igf coloured by chain, side view.
PDB entry 1igf coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A.
Stanfield RL, Fieser TM, Lerner RA, Wilson IA
Science 248 712-9 (1990)
PMID: 2333521

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213023 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
IGG1-KAPPA B13I2 FAB (LIGHT CHAIN) Chains: L, M
Molecule details ›
Chains: L, M
Length: 219 amino acids
Theoretical weight: 24.15 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins
IGG1-KAPPA B13I2 FAB (HEAVY CHAIN) Chains: H, J
Molecule details ›
Chains: H, J
Length: 221 amino acids
Theoretical weight: 23.81 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 98Å b: 151.7Å c: 80.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.18 not available
Expression system: Not provided

Quick links

Citations

27 review citations

The impact of glycosylation on the biological function and structure of human immunoglobulins.
Arnold et al. (2007)
26 more

7 mentions without citation

Crystal structure of Plasmodium knowlesi apical membrane antigen 1 and its complex with an invasion-inhibitory monoclonal antibody.
Vulliez-Le Normand et al. (2015)
6 more