› 1im7

Solution NMR

Solution structure of synthetic cyclic peptide mimicking the loop of HIV-1 gp41 glycoprotein envelope

Released:
DOI: 10.2210/pdb1im7/pdb
PDB entry 1im7 coloured by chain, front view.
PDB entry 1im7 coloured by chain, side view.
PDB entry 1im7 coloured by chain, top view.
Source organism: Human immunodeficiency virus type 1 (BRAIN ISOLATE)
Primary publication:
Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein.
Du AP, Limal D, Semetey V, Dali H, Jolivet M, Desgranges C, Cung MT, Briand JP, Petit MC, Muller S
J Mol Biol 323 503-21 (2002)
PMID: 12381305

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146174 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.38 KDa
Source organism: Human immunodeficiency virus type 1 (BRAIN ISOLATE)
Expression system: Not provided
UniProt:
  • Canonical: P12488 (Residues: 591-603; Coverage: 2%)
Gene name: env

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics energy minimisation
Expression system: Not provided

Quick links

Citations

1 review citation

More than one reason to rethink the use of peptides in vaccine design.
Purcell et al. (2007)
9 other articles

5 mentions without citation

PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides.
Thévenet et al. (2012)
4 more