› 1iq9

X-ray diffraction
1.8Å resolution

crystal structure at 1.8 A of toxin a from Naja nigricollis venom

Released:
DOI: 10.2210/pdb1iq9/pdb
PDB entry 1iq9 coloured by chain, front view.
PDB entry 1iq9 coloured by chain, side view.
PDB entry 1iq9 coloured by chain, top view.
Source organism: Naja nigricollis
Primary publication:
Motions and structural variability within toxins: implication for their use as scaffolds for protein engineering.
Gilquin B, Bourgoin M, Ménez R, Le Du MH, Servent D, Zinn-Justin S, Ménez A
Protein Sci 12 266-77 (2003)
PMID: 12538890

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134310 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Short neurotoxin 1 Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 6.81 KDa
Source organism: Naja nigricollis
UniProt:
  • Canonical: P01426 (Residues: 1-61; Coverage: 100%)
Sequence domains: Snake toxin cobra-type
Structure domains: CD59

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P43212
Unit cell:
a: 40.9Å b: 40.9Å c: 73.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.19 0.24

Quick links

Citations

3 review citations

Diversity of folds in animal toxins acting on ion channels.
Mouhat et al. (2004)
2 more

6 mentions without citation

Structural and functional characterization of a novel homodimeric three-finger neurotoxin from the venom of Ophiophagus hannah (king cobra).
Roy et al. (2010)
5 more