› 1ivv

X-ray diffraction
2.1Å resolution

Crystal structure of copper amine oxidase from Arthrobacter globiformis: Early intermediate in topaquinone biogenesis

Released:
DOI: 10.2210/pdb1ivv/pdb
PDB entry 1ivv coloured by chain, front view.
PDB entry 1ivv coloured by chain, side view.
PDB entry 1ivv coloured by chain, top view.
Source organism: Arthrobacter globiformis
Primary publication:
X-ray snapshots of quinone cofactor biogenesis in bacterial copper amine oxidase.
Kim M, Okajima T, Kishishita S, Yoshimura M, Kawamori A, Tanizawa K, Yamaguchi H
Nat Struct Biol 9 591-6 (2002)
PMID: 12134140

Function and Biology Details

Reaction catalysed: 
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155528 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phenylethylamine oxidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 638 amino acids
Theoretical weight: 70.74 KDa
Source organism: Arthrobacter globiformis
Expression system: Escherichia coli
UniProt:
  • Canonical: P46881 (Residues: 1-638; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CU 2 x CU
1 modified residue:
Ligand DAH 2 x DAH

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44B2
Unit cell:
a: 157.802Å b: 63.069Å c: 183.461Å
α: 90° β: 111.64° γ: 90°
R-values:
R R work R free
0.193 0.19 0.263
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Intrigues and intricacies of the biosynthetic pathways for the enzymatic quinocofactors: PQQ, TTQ, CTQ, TPQ, and LTQ.
Klinman et al. (2014)
8 more

4 mentions without citation

Copper active sites in biology.
Solomon et al. (2014)
3 more