› 1j6p

X-ray diffraction
1.9Å resolution

Crystal structure of Metal-dependent hydrolase of cytosinedemaniase/chlorohydrolase family (TM0936) from Thermotoga maritima at 1.9 A resolution

Released:
DOI: 10.2210/pdb1j6p/pdb
PDB entry 1j6p coloured by chain, front view.
PDB entry 1j6p coloured by chain, side view.
PDB entry 1j6p coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reactions catalysed: 
S-adenosyl-L-homocysteine + H(2)O = S-inosyl-L-homocysteine + NH(3)
S-methyl-5'-thioadenosine + H(2)O = S-methyl-5'-thioinosine + NH(3)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-194672 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-methylthioadenosine/S-adenosylhomocysteine deaminase Chain: A
Molecule details ›
Chain: A
Length: 418 amino acids
Theoretical weight: 48.04 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X034 (Residues: 1-406; Coverage: 100%)
Gene names: TM_0936, mtaD
Sequence domains: Amidohydrolase family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand NI 1 x NI
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P3221
Unit cell:
a: 113.782Å b: 113.782Å c: 81.305Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.175 0.202
Expression system: Escherichia coli

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