› 1joh

X-ray diffraction
1.4Å resolution

THE STRUCTURE OF ANTIAMOEBIN I, A MEMBRANE-ACTIVE PEPTIDE

Released:
DOI: 10.2210/pdb1joh/pdb
PDB entry 1joh coloured by chain, front view.
PDB entry 1joh coloured by chain, side view.
PDB entry 1joh coloured by chain, top view.
Source organism: Emericellopsis
Primary publication:
The structure and function of antiamoebin I, a proline-rich membrane-active polypeptide.
Snook CF, Woolley GA, Oliva G, Pattabhi V, Wood SF, Blundell TL, Wallace BA
Structure 6 783-92 (1998)
PMID: 9655831

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162268 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ANTIAMOEBIN I Chains: A, B
Molecule details ›
Chains: A, B
Length: 17 amino acids
Theoretical weight: 1.65 KDa
Source organism: Emericellopsis

Ligands and Environments

1 bound ligand:
Ligand MOH 23 x MOH
4 modified residues:
Ligand AIB 12 x AIB
Ligand DIV 4 x DIV
Ligand HYP 4 x HYP
Ligand PHL 2 x PHL

Experiments and Validation Details

Entry percentile scores
Spacegroup: P1
Unit cell:
a: 26.53Å b: 28.82Å c: 9.06Å
α: 88.9° β: 96.64° γ: 123.85°
R-values:
R R work R free
0.156 not available not available

Quick links

Citations

7 review citations

Common structural features in gramicidin and other ion channels.
Wallace BA. (2000)
6 more

2 mentions without citation

The role of hydrophobic interactions in positioning of peripheral proteins in membranes.
Lomize et al. (2007)
1 more