› 1kbd

Solution NMR

SOLUTION STRUCTURE OF A 16 BASE-PAIR DNA RELATED TO THE HIV-1 KAPPA B SITE

Released:
DOI: 10.2210/pdb1kbd/pdb
PDB entry 1kbd coloured by chain, ensemble of 3 models, front view.
PDB entry 1kbd coloured by chain, ensemble of 3 models, side view.
PDB entry 1kbd coloured by chain, ensemble of 3 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a non-palindromic 16 base-pair DNA related to the HIV-1 kappa B site: evidence for BI-BII equilibrium inducing a global dynamic curvature of the duplex.
Tisné C, Hantz E, Hartmann B, Delepierre M
J Mol Biol 279 127-42 (1998)
PMID: 9636705

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114072 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*CP*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*AP*GP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 16 nucleotides
Theoretical weight: 4.93 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*CP*CP*TP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*CP*AP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 16 nucleotides
Theoretical weight: 4.87 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

3 review citations

Transcriptional regulation via the NF-kappaB signaling module.
Hoffmann et al. (2006)
2 more

1 mention without citation

Duplex DNA Retains the Conformational Features of Single Strands: Perspectives from MD Simulations and Quantum Chemical Computations.
Capobianco et al. (2022)