› 1kjs

Solution NMR

NMR SOLUTION STRUCTURE OF C5A AT PH 5.2, 303K, 20 STRUCTURES

Released:
DOI: 10.2210/pdb1kjs/pdb
PDB entry 1kjs coloured by chain, ensemble of 20 models, front view.
PDB entry 1kjs coloured by chain, ensemble of 20 models, side view.
PDB entry 1kjs coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural definition of the C5a C terminus by two-dimensional nuclear magnetic resonance spectroscopy.
Zhang X, Boyar W, Toth MJ, Wennogle L, Gonnella NC
Proteins 28 261-7 (1997)
PMID: 9188742

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133860 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C5a anaphylatoxin Chain: A
Molecule details ›
Chain: A
Length: 74 amino acids
Theoretical weight: 8.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01031 (Residues: 679-751; Coverage: 4%)
Gene names: C5, CPAMD4
Sequence domains: Anaphylotoxin-like domain
Structure domains: Anaphylotoxins (complement system)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: AB INITIO SIMULATED ANNEALING
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Complement System Part I - Molecular Mechanisms of Activation and Regulation.
Merle et al. (2015)
7 more

32 mentions without citation

Complement evasion by human pathogens.
Lambris et al. (2008)
31 more