› 1kpv

X-ray diffraction
1.71Å resolution

High resolution crystal structure of the MHC class I complex H-2Kb/SEV9

Released:
DOI: 10.2210/pdb1kpv/pdb
PDB entry 1kpv coloured by chain, front view.
PDB entry 1kpv coloured by chain, side view.
PDB entry 1kpv coloured by chain, top view.
Source organisms:
Entry authors: Rudolph MG, Wilson IA

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
hetero trimer (preferred)
hetero hexamer
PDBe Complex ID:
PDB-CPX-135042 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
H-2 class I histocompatibility antigen, K-B alpha chain Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 31.65 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P01901 (Residues: 22-295; Coverage: 79%)
Gene names: H2-K, H2-K1
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.7 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P01887 (Residues: 21-119; Coverage: 100%)
Gene name: B2m
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Nucleoprotein Chain: P
Molecule details ›
Chain: P
Length: 9 amino acids
Theoretical weight: 949 Da
Source organism: Sendai virus (strain Enders)
Expression system: Not provided
UniProt:
  • Canonical: P04857 (Residues: 324-332; Coverage: 2%)
Gene names: N, NP

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
2 bound ligands:
Ligand PO4 2 x PO4
Ligand MPD 3 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P21212
Unit cell:
a: 136.287Å b: 88.342Å c: 45.322Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.187 0.204
Expression systems:
  • Drosophila melanogaster
  • Not provided

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