› 1kq8

Solution NMR

Solution Structure of Winged Helix Protein HFH-1

Released:
DOI: 10.2210/pdb1kq8/pdb
PDB entry 1kq8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1kq8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1kq8 coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Structure comparison of two conserved HNF-3/fkh proteins HFH-1 and genesis indicates the existence of folding differences in their complexes with a DNA binding sequence.
Sheng W, Rance M, Liao X
Biochemistry 41 3286-93 (2002)
PMID: 11876636

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179003 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Forkhead box protein Q1 Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 11.8 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q63244 (Residues: 114-213; Coverage: 25%)
Gene names: Foxq1, Hfh1
Sequence domains: Forkhead domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Structure/function relationships underlying regulation of FOXO transcription factors.
Obsil et al. (2008)
2 more