› 1kt6

X-ray diffraction
1.1Å resolution

Crystal structure of bovine holo-RBP at pH 9.0

Released:
DOI: 10.2210/pdb1kt6/pdb
PDB entry 1kt6 coloured by chain, front view.
PDB entry 1kt6 coloured by chain, side view.
PDB entry 1kt6 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
High-resolution structures of retinol-binding protein in complex with retinol: pH-induced protein structural changes in the crystal state.
Calderone V, Berni R, Zanotti G
J Mol Biol 329 841-50 (2003)
PMID: 12787682

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148473 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinol-binding protein 4 Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 21.1 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P18902 (Residues: 1-183; Coverage: 100%)
Gene name: RBP4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand RTL 1 x RTL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 46.861Å b: 48.948Å c: 75.654Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.188 0.223

Quick links

Citations

1 review citation

Loading efficacy and binding analysis of retinoids with milk proteins: a short review.
Agudelo et al. (2018)
15 other articles