› 1llq

X-ray diffraction
2.3Å resolution

Crystal Structure of Malic Enzyme from Ascaris suum Complexed with Nicotinamide Adenine Dinucleotide

Released:
DOI: 10.2210/pdb1llq/pdb
PDB entry 1llq coloured by chain, front view.
PDB entry 1llq coloured by chain, side view.
PDB entry 1llq coloured by chain, top view.
Source organism: Ascaris suum
Primary publication:
Crystal structure of the malic enzyme from Ascaris suum complexed with nicotinamide adenine dinucleotide at 2.3 A resolution.
Coleman DE, Rao GS, Goldsmith EJ, Cook PF, Harris BG
Biochemistry 41 6928-38 (2002)
PMID: 12033925

Function and Biology Details

Reaction catalysed: 
(S)-malate + NAD(+) = pyruvate + CO(2) + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151006 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NAD-dependent malic enzyme, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 605 amino acids
Theoretical weight: 68.56 KDa
Source organism: Ascaris suum
UniProt:
  • Canonical: P27443 (Residues: 39-643; Coverage: 94%)
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 2 x NAD
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P3121
Unit cell:
a: 130.62Å b: 130.62Å c: 149.23Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.247 0.247 0.28

Quick links

Citations

1 review citation

Biochemical approaches to C4 photosynthesis evolution studies: the case of malic enzymes decarboxylases.
Saigo et al. (2013)
27 other articles

4 mentions without citation

The Blueprint of a Minimal Cell: MiniBacillus.
Reuß et al. (2016)
3 more