1mk9

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-138489 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin beta-3 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 16 amino acids
Theoretical weight: 1.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05106 (Residues: 765-776; Coverage: 2%)
Gene names: GP3A, ITGB3
Talin-1 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 192 amino acids
Theoretical weight: 22.15 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P54939 (Residues: 209-400; Coverage: 8%)
Gene names: TLN, TLN1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-D
Spacegroup: P21
Unit cell:
a: 50.257Å b: 141.763Å c: 59.597Å
α: 90° β: 90.11° γ: 90°
R-values:
R R work R free
0.242 0.242 0.327
Expression system: Escherichia coli BL21(DE3)