Function and Biology Details
Reactions catalysed:
A carboxylic ester + H(2)O = an alcohol + a carboxylate
A steryl ester + H(2)O = a sterol + a fatty acid
4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
homo hexamer (preferred)
Assembly name:
Liver carboxylesterase 1 (preferred)
PDBe Complex ID:
PDB-CPX-149883 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Liver carboxylesterase 1
Molecule details ›
Chains: A, B, C, D, E, F
Length: 548 amino acids
Theoretical weight: 60.51 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Carboxylesterase family
Structure domains: alpha/beta hydrolase
Length: 548 amino acids
Theoretical weight: 60.51 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P23141 (Residues: 19-567; Coverage: 100%)
Sequence domains: Carboxylesterase family
Structure domains: alpha/beta hydrolase
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
SSRL BEAMLINE BL9-1
Spacegroup:
P21
Expression system: Spodoptera frugiperda
