› 1n3q

X-ray diffraction
2.2Å resolution

Pterocarpus angolensis lectin complexed with turanose

Released:
DOI: 10.2210/pdb1n3q/pdb
PDB entry 1n3q coloured by chain, front view.
PDB entry 1n3q coloured by chain, side view.
PDB entry 1n3q coloured by chain, top view.
Source organism: Pterocarpus angolensis
Primary publication:
Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose.
Loris R, Imberty A, Beeckmans S, Van Driessche E, Read JS, Bouckaert J, De Greve H, Buts L, Wyns L
J Biol Chem 278 16297-303 (2003)
PMID: 12595543

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184567 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Legume lectin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 27.58 KDa
Source organism: Pterocarpus angolensis
UniProt:
  • Canonical: Q8GSD2 (Residues: 9-260; Coverage: 97%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: FRU, GLC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: GLC, BDF
Carbohydrate polymer
2 bound ligands:
Ligand MN 2 x MN
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X31
Spacegroup: P212121
Unit cell:
a: 56.66Å b: 83.23Å c: 123.16Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.184 0.238

Quick links

Citations

5 review citations

Mannose-Specific Lectins from Marine Algae: Diverse Structural Scaffolds Associated to Common Virucidal and Anti-Cancer Properties.
Barre et al. (2019)
4 more

1 mention without citation

Increasing vaccine production using pulsed ultrasound waves.
Xing et al. (2017)