› 1nxr

Solution NMR

HIV-1 POLYPURINE HYBRID, R(GAGGACUG):D(CAGTCCTC), NMR, 18 STRUCTURES

Released:
DOI: 10.2210/pdb1nxr/pdb
PDB entry 1nxr coloured by chain, ensemble of 18 models, front view.
PDB entry 1nxr coloured by chain, ensemble of 18 models, side view.
PDB entry 1nxr coloured by chain, ensemble of 18 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of r(gaggacug):d(CAGTCCTC) hybrid: implications for the initiation of HIV-1 (+)-strand synthesis.
Fedoroff OY, Ge Y, Reid BR
J Mol Biol 269 225-39 (1997)
PMID: 9191067

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-114286 (preferred)
Entry contents:
1 distinct DNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
DNA (5'-D(*CP*AP*GP*TP*CP*CP*TP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 8 nucleotides
Theoretical weight: 2.36 KDa
Source organism: Synthetic construct
Expression system: Not provided
RNA (5'-R(*GP*AP*GP*GP*AP*CP*UP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 8 nucleotides
Theoretical weight: 2.61 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, : RESTRAINED MOLECULAR : DYNAMICS
Expression system: Not provided

Quick links

Citations

4 review citations

Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition.
Sarafianos et al. (2009)
3 more

1 mention without citation

Exploring DNA structure with Cn3D.
Porter et al. (2007)