› 1or3

X-ray diffraction
1.73Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apolipoprotein E Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 19.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02649 (Residues: 19-183; Coverage: 55%)
Gene name: APOE
Sequence domains: Apolipoprotein A1/A4/E domain
Structure domains: Apolipoprotein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3121
Unit cell:
a: 47.37Å b: 47.37Å c: 104.54Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.229 0.229 0.238
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies.
Yamazaki et al. (2019)
3 more

5 mentions without citation

Hepatitis A Virus Genome Organization and Replication Strategy.
McKnight et al. (2018)
4 more