› 1pbx

X-ray diffraction
2.5Å resolution

HAEMOGLOBIN OF THE ANTARCTIC FISH PAGOTHENIA BERNACCHII: AMINO ACID SEQUENCE, OXYGEN EQUILIBRIA AND CRYSTAL STRUCTURE OF ITS CARBONMONOXY DERIVATIVE

Released:
DOI: 10.2210/pdb1pbx/pdb
PDB entry 1pbx coloured by chain, front view.
PDB entry 1pbx coloured by chain, side view.
PDB entry 1pbx coloured by chain, top view.
Source organism: Trematomus bernacchii
Primary publication:
Haemoglobin of the antarctic fish Pagothenia bernacchii. Amino acid sequence, oxygen equilibria and crystal structure of its carbonmonoxy derivative.
Camardella L, Caruso C, D'Avino R, di Prisco G, Rutigliano B, Tamburrini M, Fermi G, Perutz MF
J Mol Biol 224 449-60 (1992)
PMID: 1560461

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160338 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 15.68 KDa
Source organism: Trematomus bernacchii
Expression system: Not provided
UniProt:
  • Canonical: P80043 (Residues: 1-142; Coverage: 100%)
Gene name: hba
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chain: B
Molecule details ›
Chain: B
Length: 146 amino acids
Theoretical weight: 16.15 KDa
Source organism: Trematomus bernacchii
Expression system: Not provided
UniProt:
  • Canonical: P80044 (Residues: 2-147; Coverage: 99%)
Gene name: hbb
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 2 x HEM
Ligand CMO 2 x CMO
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 91.38Å b: 88.54Å c: 55.34Å
α: 90° β: 97.16° γ: 90°
R-values:
R R work R free
0.178 0.178 not available
Expression system: Not provided

Quick links

Citations

5 review citations

Cold-adapted enzymes.
Marshall CJ. (1997)
4 more

4 mentions without citation

The crystal structure of a tetrameric hemoglobin in a partial hemichrome state.
Riccio et al. (2002)
3 more