› 1pvv

X-ray diffraction
1.87Å resolution

Refined Structure of Pyrococcus furiosus Ornithine Carbamoyltransferase at 1.87 A

Released:
DOI: 10.2210/pdb1pvv/pdb
PDB entry 1pvv coloured by chain, front view.
PDB entry 1pvv coloured by chain, side view.
PDB entry 1pvv coloured by chain, top view.
Source organism: Pyrococcus furiosus
Primary publication:
Refined structure of Pyrococcus furiosus ornithine carbamoyltransferase at 1.87 A.
Massant J, Wouters J, Glansdorff N
Acta Crystallogr D Biol Crystallogr 59 2140-9 (2003)
PMID: 14646072

Function and Biology Details

Reaction catalysed: 
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175969 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ornithine carbamoyltransferase, anabolic Chain: A
Molecule details ›
Chain: A
Length: 315 amino acids
Theoretical weight: 35.23 KDa
Source organism: Pyrococcus furiosus
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q51742 (Residues: 1-315; Coverage: 100%)
Gene names: PF0594, argF
Sequence domains:
Structure domains: Aspartate/ornithine carbamoyltransferase

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: F23
Unit cell:
a: 184.777Å b: 184.777Å c: 184.777Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.213 0.269
Expression system: Saccharomyces cerevisiae

Quick links

Citations

1 review citation

From Genome to Structure and Back Again: A Family Portrait of the Transcarbamylases.
Shi et al. (2015)
8 other articles

7 mentions without citation

The role of non-native interactions in the folding of knotted proteins: insights from molecular dynamics simulations.
Covino et al. (2013)
6 more