Function and Biology Details
Reaction catalysed:
(S)-lactate + NAD(+) = pyruvate + NADH
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
L-lactate dehydrogenase (preferred)
PDBe Complex ID:
PDB-CPX-161038 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
L-lactate dehydrogenase
Molecule details ›
Chain: A
Length: 331 amino acids
Theoretical weight: 35.74 KDa
Source organism: Toxoplasma gondii ME49
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 331 amino acids
Theoretical weight: 35.74 KDa
Source organism: Toxoplasma gondii ME49
Expression system: Escherichia coli
UniProt:
- Canonical:
P90613 (Residues: 1-329; Coverage: 100%)
Sequence domains:
- lactate/malate dehydrogenase, NAD binding domain
- lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL9-1
Spacegroup:
I4122
Expression system: Escherichia coli
