› 1q9h

X-ray diffraction
2.35Å resolution

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186269 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Glucanase Chain: A
Molecule details ›
Chain: A
Length: 437 amino acids
Theoretical weight: 46.85 KDa
Source organism: Rasamsonia emersonii
UniProt:
  • Canonical: Q8TFL9 (Residues: 19-455; Coverage: 100%)
Gene names: cbh1, cbh1A
Sequence domains: Glycosyl hydrolase family 7
Structure domains: Glycoside hydrolase, family 7, domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P41212
Unit cell:
a: 74.395Å b: 74.395Å c: 177.046Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.161 0.229

Quick links

Citations

6 review citations

Fungal bioconversion of lignocellulosic residues; opportunities & perspectives.
Dashtban et al. (2009)
5 more

10 mentions without citation

Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii.
Grassick et al. (2004)
9 more