› 1r6j

X-ray diffraction
0.73Å resolution

Ultrahigh resolution Crystal Structure of syntenin PDZ2

Released:
DOI: 10.2210/pdb1r6j/pdb
PDB entry 1r6j coloured by chain, front view.
PDB entry 1r6j coloured by chain, side view.
PDB entry 1r6j coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The PDZ2 domain of syntenin at ultra-high resolution: bridging the gap between macromolecular and small molecule crystallography.
Kang BS, Devedjiev Y, Derewenda U, Derewenda ZS
J Mol Biol 338 483-93 (2004)
PMID: 15081807

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126342 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Syntenin-1 Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 8.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O00560 (Residues: 197-273; Coverage: 26%)
Gene names: MDA9, SDCBP, SYCL
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P21
Unit cell:
a: 25.876Å b: 39.544Å c: 32.276Å
α: 90° β: 109.64° γ: 90°
R-values:
R R work R free
0.075 0.075 0.087
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

Do all backbone polar groups in proteins form hydrogen bonds?
Fleming et al. (2005)
1 more

22 mentions without citation

The "Sticky Patch" Model of Crystallization and Modification of Proteins for Enhanced Crystallizability.
Derewenda et al. (2017)
21 more